Bioproduction and extraction of jasmonates

Introduction Jasmonates are a growing class of compounds of vegetable origin which present phytoregulator activity and toxicity against some types of cancer cells. Additionally the jasmonates have also shown activity against some types of nematodes [1]. Jasmonates available on the market are of plant origin or synthetic, present costs are still high. Like plants, some microorganisms have the potential to produce jasmonates. Some microorganisms have the potential to produce this class of compounds, including filamentous fungus Botryosphaeria rhodina has shown to be the most promising. The choice of the strain and optimization of process steps are fundamental premises for increasing the scale of production [2]. Furthermore, the optimization of the steps of extraction and purification of the product in the fermentation broth are essential to ensure the viability of the process. Currently, studies of recovery of jasmonates produced by Botryosphaeria rhodina are based on organic solvents. In this work, an alternative recovery route is proposed, based on adsorption, and the determination of the adsorption kinetics of jasmonates present in fermented using ion exchange resins Amberlite ® is presented.